FIGURE 1.

Remdesivir, an investigational nucleotide analogue, and its triphosphate possessing resemblance with Adenosine triphosphate can compete with it to act as a substrate for various viral RNA polymerase inhibiting RNA synthesis. Remdesivir triphosphate form adds to the growing RNA chain more efficiently than ATP, causing chain termination at 3 nucleotides downstream, and displays anti-COVID-19 efficacy.