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The Ploemen and modified Ploemen criteria for prediction of phospholipidosis
| Ploemen Model | Modified Ploemen Model | |
|---|---|---|
| Predicted positive | If (pKa-basic)2 + (ClogP)2 ≥ 90, provided that pKa ≥ 8 and ClogP ≥ 1 | If (pKa-basic)2 + (ClogP)2 ≥ 50, provided that pKa ≥ 6 and ClogP ≥ 2 |
| Predicted negative | When result < 90 or pKa < 8 or ClogP < 1 | When result < 50 or pKa < 6 or ClogP < 2 |
