TABLE 2.
Baseline characteristics according to treatment assignment1
| EPA+DHA (n = 138) | Control (n = 130) | P value | |
|---|---|---|---|
| Demographic characteristics | |||
| Age, y | 62.9 ± 7.6 | 63.9 ± 7.4 | 0.27 |
| Male sex | 115 (83.3) | 108 (83.1) | 0.82 |
| Diabetics | 39 (28.3) | 40 (30.8) | 0.81 |
| Anthropometrics and blood pressure | |||
| Weight, kg | 91.8 ± 13.6 | 90.2 ± 15.2 | 0.48 |
| BMI,2 kg/m2 | 30.8 ± 3.6 | 30.6 ± 3.7 | 0.66 |
| Waist, cm | 106.9 ± 10.3 | 106.7 ± 11.2 | 0.71 |
| Systolic BP, mm Hg | 125.1 ± 14.6 | 124.4 ± 14.8 | 0.88 |
| Diastolic BP, mm Hg | 73.1 ± 10.0 | 72.4 ± 8.9 | 0.84 |
| Biochemical profile | |||
| HbA1c, % | 6.1 ± 0.8 | 6.3 ± 1.1 | 0.27 |
| Glucose, mg/dL | 104.8 ± 27.4 | 108.6 ± 37.3 | 0.29 |
| Lipid concentrations,3 mg/dL | |||
| Total cholesterol | 152.5 ± 37.5 | 152.1 ± 34.0 | 0.76 |
| LDL-C | 77.7 ± 26.9 | 78.2 ± 28.3 | 0.35 |
| HDL-C | 47.2 ± 14.8 | 46.8 ± 14.4 | 0.72 |
| Triglyceride | 121.5 [80.3–178.8] | 114.0 [78.0–161.0] | 0.44 |
| Inflammatory markers | |||
| hs-CRP, mg/L | 1.0 [0.4–2.5] | 1.0 [0.4–3.1] | 0.08 |
| WBC, 109 cells/L | 6.6 ± 2.0 | 6.6 ± 1.6 | 0.59 |
| Monocytes, cells/μL | 542.3 ± 173.0 | 516.9 ± 170.7 | 0.16 |
| Neutrophils, cells/μL | 4238.9 ± 1767.5 | 4192.4 ± 1341.1 | 0.74 |
| Lymphocytes, cells/μL | 1629.9 ± 557.6 | 1694.6 ± 632.6 | 0.23 |
| Medications | |||
| Statin therapy | 133 (96.4) | 123 (94.6) | 0.37 |
| Aspirin | 133 (96.4) | 124 (95.4) | 0.53 |
Values are mean ± SD, n (%), or median [IQR]. Categorical variables (male sex and diabetes) were expressed as n (%) and compared using the chi-square test. All normally distributed continuous variables were compared using unpaired t tests except for triglyceride and hs-CRP, which were compared with the Wilcoxon–Mann–Whitney U test because they were nonnormally distributed variables. BP, blood pressure; HbA1C, glycated hemoglobin; HDL-C, HDL cholesterol; hs-CRP, high-sensitivity C-reactive protein; LDL-C, LDL cholesterol; WBC, white blood cell.
Calculated as weight in kilograms divided by height in meters squared.
Multiply by 0.02586 to convert cholesterol values to mmol/L and by 0.01129 to convert triglyceride to mmol/L.