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. 2021 Jun 30;21:303. doi: 10.1186/s12893-021-01298-w

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Principal component analysis (PCA) of differentially expressed genes (DEGs) between intact skin samples and the wound sample at different phases. Genes were plotted in 3D visualization, indicating that samples within each group shared more similarity. A The red dots showed the PCA values of 8 intact skin samples (IS), and the green dots indicate the PCA value of 6 acute wounds samples (AW), and the blue dots indicate the PCA value of 6 third-postoperative-day samples (3rd POD), and the yellow dots indicate the PCA value of 5 seventh-postoperative-day samples (7th POD) from GSE28914. B The red dots showed the PCA values of 4 intact skin samples (IS), and the green dots indicate the PCA value of 4 fourteenth-postoperative-day samples (14th POD), and the blue dots indicate the PCA value of 4 twenty first-postoperative-day samples (21st POD) from GSE50425