Table 2.
Difference in respiratory and hemodynamic variables between groups
| Parameters | Day 0 | Day 1 | Day 2 | Day 3 | Trend p value |
|---|---|---|---|---|---|
| VT (ml) of PC mode | |||||
| EIT group | 414 (383, 460) | 450 (390, 520) * | 430(373, 490) | 429 (364, 497) | 0.306 |
| Control group | 407 (362, 463) | 410(370, 445) | 411(370, 481) | 426 (345, 485) | 0.153 |
| Driving pressure (cmH2O) | |||||
| EIT group | 14(11, 15) | 13(11, 15) | 13(11, 15) | 13 (11, 15) | 0.631 |
| Control group | 13 (11, 15) | 13 (12, 14) | 12(11.0, 15) | 13 (10, 15) | 0.772 |
| Pmean (cmH2O) | |||||
| EIT group | 10 (9, 12) | 12 (10, 14) | 12 (10, 14) | 12 (10, 14) | 0.065 |
| Control group | 10 (9, 12) | 11 (10, 13) | 12 (9, 13) | 11 (10, 13) | 0.445 |
| RR (bpm) | |||||
| EIT group | 15 (15, 15) | 15(14, 18) | 16(15, 20) | 18 (14, 22) | < 0.0001 |
| Control group | 15 (15, 16) | 16(15, 18) | 15(15, 18) | 17 (14, 20) | < 0.0001 |
| Respiratory compliance (ml/cmH2O) | |||||
| EIT group | 32 (27, 41) | 33 (25, 43) | 31 (25, 38) | 33 (25, 43) | 0.239 |
| Control group | 30 (24, 37) | 30 (24, 37) | 30 (24, 40) | 33 (24, 43) | 0.150 |
| PEEP (cmH2O) | |||||
| EIT group | 8 (6, 9) | 8 (6, 9) | 8 (6,9) | 8 (6, 9) | 0.287 |
|
Control group pH |
8 (5, 10) | 8 (6, 9) | 8 (6, 9) | 7 (6, 9) | 0.249 |
| EIT group | 7.4 (7.3, 7.4) | 7.4 (7.4, 7.5) | 7.4 (7.4, 7.5) | 7.4 (7.4, 7.5) | < 0.0001 |
| Control group | 7.4 (7.3, 7.4) | 7.4 (7.4, 7.5) | 7.5 (7.4, 7.5) | 7.5 (7.4, 7.5) | < 0.0001 |
| PaCO2 (mmHg) | |||||
| EIT group | 39 (36, 46) | 39 (38, 43) | 42 (39, 46) | 41 (38, 44) | 0.239 |
| Control group | 40 (35, 43) | 41(39, 44) | 39 (37, 43) | 40 (38, 43) | 0.817 |
| PaO2 (mmHg) | |||||
| EIT group | 82 (74, 96) | 92 (76, 104) | 91 (79, 110) | 96 (79, 118) | 0.183 |
| Control group | 88 (70, 122) | 93 (79, 111) | 96 (74, 114) | 95 (78, 116) | 0.984 |
| PaO2/FiO2 (mmHg) | |||||
| EIT group | 165 (106, 213) | 187 (144, 242) | 214 (165, 283) | 220 (170, 295) | < 0.0001 |
| Control group | 176 (139, 222) | 212 (170, 269) | 232 (155, 316) | 231 (180, 295) | 0.001 |
| Lactate (mmol/L) | |||||
| EIT group | 2.2 (1.4, 4.7) | 1.9 (1.2, 2.9) | 1.2 (1.0, 2.0) | 1.3 (0.9, 1.6) | < 0.0001 |
| Control group | 2.0 (1.4, 4.0) | 2.0 (1.2, 2.8) | 1.6 (1.1, 2.1) | 1.4 (1.1, 1.8) | < 0.0001 |
| APACHE II | |||||
| EIT group | 19 (14,25) | 18 (12, 24) | 15 (12, 21) | 16 (12, 19) | < 0.0001 |
| Control group | 17 (14,20) | 18 (16, 21) | 16 (13, 21) | 15 (13, 20) | < 0.0001 |
| SOFA | |||||
| EIT group | 13 (11, 14) | 12 (10, 14) | 11 (9, 13) | 11 (9,13) | < 0.0001 |
| Control group | 12 (9, 13) | 12 (11, 14) | 12 (10, 14) | 12 (10,14) | 0.022 |
*EIT group versus control group, p < 0.05. VT, tidal volume; PC, pressure control mode; Pmean, mean airway pressure; RR, respiratory rate; PEEP, positive end-expiratory pressure; APACHE II, Acute Physiology and Chronic Health Evaluation; SOFA, Sequential Organ Failure Assessment