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Parameters of renal function in rats. (A) Kidney index (kidney weight/body weight), (B) Scr, (C) BUN, (D) Urine protein, (E) Urine microalbumin. Plasma TMAO levels were significantly correlated with renal function parameters Scr (F), BUN (G), Urine protein (H), and Urine microalbumin (I). Data are presented as mean ± SEM (n = 8 for each group). #P < 0.05, ##P < 0.01, ###P < 0.001 vs. CON, ∗P < 0.05, ∗∗P < 0.01 vs. DKD.
