Table 1.
Experimental studies that investigated the role of piRNAs in colorectal cancer
| PiRNA | Model | Expression | Function | References |
|---|---|---|---|---|
| PiR-823 | In vitro | Up-regulated | Associated with the expression of HSP family | [108] |
| PiR-54265 | In vitro | Up-regulated | Activating STAT3 signaling | [111] |
| PiR-651 | In vitro | Up-regulated | Associated with T stage, metastasis | [91] |
| PiR‐54,878 | In vitro | Up-regulated | Associated with recurrence-free survival | [90] |
| PiR-59056 | In vitro | Up-regulated | Associated with recurrence-free survival | [90] |
| PiR-62701 | In vitro | Up-regulated | Associated with recurrence-free survival | [90] |
| PiR-015551 | In vitro | Down-regulated | Associated with LNC00964-3 expression level | [71] |
| PiR-1245 | In vitro | Down-regulated | Associated with advanced and metastatic disease | [113] |