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. 2021 Jun 29;21:751. doi: 10.1186/s12885-021-08505-0

Table 1.

Clinical characteristics of training group and validation group for overall survival analysis

Characteristic Overall Training group Verification group P
3142 2202 940
Marital status (%)
 Married 1674 (53.3) 1152 (52.3) 522 (55.5) 0.23
 Separated 734 (23.4) 521 (23.7) 213 (22.7)
 Single 734 (23.4) 529 (24.0) 205 (21.8)
Age (%)
  < 65 2009 (63.9) 1415 (64.3) 594 (63.2) 0.16
 65–75 803 (25.6) 545 (24.8) 258 (27.4)
  > 75 330 (10.5) 242 (11.0) 88 (9.4)
Sex (%)
 Female 762 (24.3) 547 (24.8) 215 (22.9) 0.26
 Male 2380 (75.7) 1655 (75.2) 725 (77.1)
Race (%)
 Other 694 (22.1) 494 (22.4) 200 (21.3) 0.68
 White 2070 (65.9) 1440 (65.4) 630 (67.0)
 Black 378 (12.0) 268 (12.2) 110 (11.7)
Histological grade (%)
 Well differentiated 455 (14.5) 311 (14.1) 144 (15.3) 0.27
 Moderately differentiated 541 (17.2) 370 (16.8) 171 (18.2)
 Poorly differentiated 133 (4.2) 103 (4.7) 30 (3.2)
 Undifferentiated 5 (0.2) 3 (0.1) 2 (0.2)
 Unknown 2008 (63.9) 1415 (64.3) 593 (63.1)
T (%)
 T1a 450 (14.3) 316 (14.4) 134 (14.3) 0.24
 T1b 1631 (51.9) 1162 (52.8) 469 (49.9)
 T2 891 (28.4) 601 (27.3) 290 (30.9)
 T3 105 (3.3) 73 (3.3) 32 (3.4)
 T4 65 (2.1) 50 (2.3) 15 (1.6)
M (%)
 M0 3105 (98.8) 2174 (98.7) 931 (99.0) 0.59
 M1 37 (1.2) 28 (1.3) 9 (1.0)
N (%)
 N0 3092 (98.4) 2173 (98.7) 919 (97.8) 0.08
 N1 50 (1.6) 29 (1.3) 21 (2.2)
Radiation therapy (%)
 Unradiation 3053 (97.2) 2137 (97.0) 916 (97.4) 0.62
 Radiation 89 (2.8) 65 (3.0) 24 (2.6)
Chemotherapy (%)
 Unchemotherapy 2129 (67.8) 1504 (68.3) 625 (66.5) 0.34
 Chemotherapy 1013 (32.2) 698 (31.7) 315 (33.5)
Tumor size (%)
 0-28 mm 1581 (50.3) 1089 (49.5) 492 (52.3) 0.28
 21-35 mm 685 (21.8) 483 (21.9) 202 (21.5)
  > 35 mm 876 (27.9) 630 (28.6) 246 (26.2)
AFP (%)
 Nomal-afp 998 (31.8) 711 (32.3) 287 (30.5) 0.35
 Up-afp 2144 (68.2) 1491 (67.7) 653 (69.5)
Fibersis (%)
 Non-fibersis 171 (5.4) 126 (5.7) 45 (4.8) 0.53
 Fibersis 1097 (34.9) 762 (34.6) 335 (35.6)
 Unknown 1874 (59.6) 1314 (59.7) 560 (59.6)
Survival months (median [IQR]) 27.00 [15.00, 49.00] 28.00 [16.00, 50.00] 27.00 [15.00, 48.00] 0.30