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. 2021 Jun 25;14:2681–2696. doi: 10.2147/JIR.S306846

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© 2021 Jiang et al.

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Euph E and Euri A inhibit NO production and iNOS expression. Cells were pretreated with Euph E or Euri A (2.5-20 μM) and then co-incubated with LPS (1 μg/mL). (A) NO production was determined by measuring the level of nitrite in culture medium. (B) The expression of iNOS protein was determined by Western blot analysis. Actin served as an internal control. The values represent the mean ± SD of three independent experiments (Supplementary Figure S7). Compared with control group, ^###P<0.001; Compared with LPS group, *P<0.05, ***P<0.001.