Table 1:
Characteristics of children with PHIV (N=213) included in this analysis.
| Valuea | |
|---|---|
| Siteb | |
| South Africa: Harriet Shezi | 25 (12%) |
| South Africa: Soweto (PHRU) | 37 (17%) |
| South Africa: Tygerberg | 48 (23%) |
| Malawi: Lilongwe | 27 (13%) |
| Uganda: Kampala | 31 (15%) |
| Zimbabwe: Harare | 45 (21%) |
| Sex | |
| Male | 92 (43%) |
| Female | 121 (57%) |
| Age at initiation of ART (yrs) | 1.2 (0.5, 2.6) |
| P1060 treatment arm | |
| NVP-based regimen | 109 (51%) |
| LPV/r-based regimen | 104 (49%) |
| Age at P1104s entry (yrs) | 7.0 (5.7, 8.7) |
| ART regimen at P1104s entry | |
| NVP-based regimen | 63 (30%) |
| LPV/r-based regimen | 143 (67%) |
| Other | 7 (3%) |
| CD4%, nadir | 14.8 (7.7, 24.6) |
| Weight z-score at P1104s entry | −0.72 (−1.91, 0.47) |
| Height z-score at P1104s entry | −1.01 (−2.24, 0.28) |
| Years aviremic before P1104s entry | 5.0 (0.8, 7.8) |
| Caregiver at entry | |
| Biological mother | 181 (85%) |
| Other | 32 (15%) |
| Socio-economic indexc | 6.1 (2.1, 10.0) |
| Premature birth (< 37 weeks) | 20 (9%) |
| Birthweight < 2000 grams | 11 (5%) |
Value corresponds to median (10th, 90th percentile) for continuous variables and frequency (percentage) for categorical variables.
All participants with PHIV in P1104s were previously enrolled in P1060 from six study sites in : South Africa (Wits RHI Shandukani clinic [Johannesburg], Chris Hani HIV Unit [Soweto], Family Clinical Research Unit [Cape Town]), Malawi (Kamuzu Central Hospital HIV clinic [Lilongwe]), Uganda (Makerere University – Johns Hopkins University Clinic Mulago National Referral Hospital [Kampala]), and Zimbabwe (Parirenyatwa General Hospital [Harare]).
The socioeconomic index is a composite of caregiver education, fuel and water sources, sufficiency of household income for basic needs, caregiver education and work status, major source of information, and whether household has a refrigerator. Values range from 0 (lower SES) to 10 (higher SES).