Table 2:
Start of controlled viremia | Week 0 | Week 48 | ||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Marker | F1 | F2 | F3 | F4 | F5 | F6 | F7 | Communality | F1 | F2 | F3 | F4 | F5 | F6 | F7 | Communality | F1 | F2 | F3 | F4 | F5 | F6 | F7 | Communality |
IFNα2 | 0.77 | −0.08 | 0.21 | −0.03 | 0.23 | −0.00 | 0.02 | 0.69 | 0.79 | 0.07 | 0.03 | −0.13 | −0.22 | 0.02 | 0.04 | 0.70 | 0.80 | 0.04 | −0.13 | 0.22 | 0.15 | −0.03 | 0.21 | 0.77 |
IFNγ | 0.76 | −0.01 | 0.23 | −0.21 | 0.02 | −0.09 | 0.13 | 0.69 | 0.82 | 0.13 | −0.12 | 0.05 | −0.03 | 0.09 | −0.09 | 0.72 | 0.88 | 0.05 | 0.07 | 0.06 | 0.04 | 0.08 | −0.04 | 0.79 |
IL-10 | 0.74 | 0.22 | 0.00 | 0.00 | 0.13 | 0.03 | −0.08 | 0.62 | 0.81 | −0.01 | −0.09 | 0.04 | 0.13 | 0.04 | 0.12 | 0.70 | 0.72 | 0.24 | 0.17 | −0.18 | 0.35 | −0.17 | −0.08 | 0.80 |
IL-1β | 0.77 | 0.02 | −0.09 | 0.23 | −0.07 | 0.07 | −0.01 | 0.66 | 0.66 | 0.17 | 0.19 | −0.16 | −0.46 | −0.18 | −0.07 | 0.77 | 0.81 | −0.08 | −0.12 | 0.23 | −0.20 | 0.11 | 0.11 | 0.80 |
IL-6 | 0.51 | 0.15 | 0.61 | 0.14 | −0.16 | −0.00 | 0.03 | 0.71 | 0.89 | 0.06 | 0.13 | −0.09 | 0.03 | 0.05 | −0.09 | 0.84 | 0.78 | −0.06 | −0.25 | −0.01 | −0.22 | 0.21 | 0.00 | 0.76 |
IP-10 | 0.89 | 0.14 | 0.15 | 0.04 | −0.04 | 0.07 | −0.04 | 0.84 | 0.90 | 0.13 | −0.02 | 0.01 | −0.01 | 0.07 | −0.08 | 0.84 | 0.85 | 0.15 | 0.12 | 0.04 | −0.03 | 0.22 | −0.01 | 0.81 |
TNFα | 0.73 | 0.22 | −0.12 | 0.22 | 0.27 | 0.04 | 0.04 | 0.73 | 0.88 | 0.12 | 0.06 | 0.05 | −0.03 | −0.03 | 0.07 | 0.80 | 0.80 | 0.06 | 0.12 | −0.03 | 0.35 | −0.05 | 0.07 | 0.79 |
sCD163 | −0.13 | 0.70 | 0.15 | 0.09 | 0.05 | 0.08 | 0.06 | 0.55 | 0.05 | 0.44 | 0.16 | 0.01 | 0.62 | −0.26 | −0.03 | 0.67 | 0.21 | 0.69 | 0.07 | −0.18 | 0.28 | −0.08 | 0.08 | 0.65 |
sICAM-1 | 0.27 | 0.79 | 0.20 | 0.00 | −0.15 | 0.05 | −0.06 | 0.76 | 0.14 | 0.85 | 0.12 | −0.13 | −0.16 | −0.04 | −0.09 | 0.81 | 0.00 | 0.86 | 0.02 | 0.12 | −0.21 | 0.23 | 0.10 | 0.86 |
sVCAM-1 | 0.39 | 0.75 | −0.10 | −0.03 | 0.00 | 0.00 | −0.04 | 0.74 | 0.10 | 0.89 | 0.11 | −0.08 | 0.06 | −0.04 | −0.04 | 0.84 | −0.05 | 0.90 | −0.10 | 0.06 | −0.01 | 0.05 | −0.03 | 0.84 |
CRP | 0.16 | 0.11 | 0.74 | 0.04 | −0.15 | 0.12 | 0.08 | 0.63 | 0.17 | 0.63 | −0.12 | 0.22 | −0.02 | 0.42 | 0.13 | 0.68 | 0.35 | 0.48 | 0.16 | 0.04 | −0.52 | 0.04 | 0.08 | 0.65 |
sCD14 | −0.04 | 0.05 | 0.84 | −0.12 | 0.11 | −0.10 | −0.01 | 0.74 | 0.10 | −0.00 | 0.16 | −0.13 | 0.04 | 0.79 | −0.08 | 0.68 | 0.27 | 0.26 | 0.29 | −0.02 | −0.38 | 0.32 | 0.40 | 0.64 |
sE-selectin | −0.06 | 0.23 | 0.19 | −0.24 | 0.32 | 0.67 | 0.17 | 0.73 | 0.04 | 0.17 | 0.63 | 0.06 | 0.08 | 0.29 | 0.01 | 0.52 | 0.01 | 0.31 | 0.40 | 0.10 | −0.22 | 0.63 | −0.09 | 0.73 |
sP-selectin | 0.05 | 0.00 | −0.11 | 0.26 | −0.07 | 0.80 | −0.06 | 0.74 | −0.07 | 0.02 | 0.83 | 0.16 | 0.05 | −0.00 | −0.03 | 0.72 | 0.23 | 0.03 | −0.14 | 0.08 | 0.20 | 0.82 | −0.03 | 0.80 |
MIP-1β | 0.17 | 0.24 | −0.12 | 0.64 | 0.01 | 0.14 | −0.16 | 0.56 | 0.54 | −0.12 | 0.40 | 0.21 | 0.09 | −0.08 | 0.22 | 0.57 | 0.16 | 0.04 | 0.20 | 0.82 | 0.17 | −0.02 | 0.00 | 0.77 |
VEGF-A | 0.32 | −0.10 | 0.01 | 0.64 | −0.05 | 0.33 | 0.11 | 0.65 | 0.15 | 0.17 | 0.45 | 0.06 | −0.51 | −0.22 | −0.05 | 0.56 | 0.06 | 0.00 | −0.19 | 0.81 | −0.03 | 0.14 | −0.06 | 0.72 |
CX3CL1 | 0.09 | −0.31 | −0.02 | 0.27 | 0.66 | −0.02 | −0.10 | 0.62 | 0.02 | −0.06 | 0.14 | 0.73 | −0.20 | 0.02 | 0.07 | 0.60 | −0.12 | −0.01 | 0.27 | 0.22 | 0.04 | 0.26 | −0.69 | 0.68 |
MCP-1 | 0.20 | 0.12 | −0.07 | −0.01 | 0.71 | 0.09 | 0.09 | 0.58 | 0.61 | 0.06 | −0.01 | 0.44 | 0.12 | 0.14 | 0.09 | 0.62 | 0.31 | 0.06 | −0.12 | 0.23 | 0.74 | 0.15 | 0.03 | 0.74 |
Fibrinogen | 0.01 | 0.07 | 0.25 | 0.18 | −0.34 | 0.31 | −0.52 | 0.58 | 0.02 | −0.11 | 0.13 | −0.20 | 0.71 | 0.07 | −0.03 | 0.58 | −0.02 | −0.15 | 0.79 | −0.09 | 0.04 | 0.12 | 0.07 | 0.67 |
MMP9 | −0.23 | −0.05 | 0.10 | 0.70 | 0.21 | −0.18 | 0.11 | 0.64 | −0.04 | −0.03 | 0.13 | 0.74 | −0.01 | −0.16 | −0.18 | 0.62 | 0.01 | 0.13 | 0.69 | 0.07 | −0.18 | −0.13 | −0.21 | 0.59 |
NFL | 0.03 | 0.02 | 0.17 | 0.09 | −0.06 | 0.13 | 0.87 | 0.81 | 0.01 | −0.05 | −0.00 | −0.08 | −0.02 | −0.06 | 0.95 | 0.92 | −0.01 | 0.07 | 0.03 | 0.08 | 0.03 | 0.06 | 0.83 | 0.71 |
Eigenvalue | 4.40 | 2.08 | 2.00 | 1.74 | 1.44 | 1.43 | 1.17 | 5.52 | 2.29 | 1.67 | 1.54 | 1.53 | 1.11 | 1.09 | 5.00 | 2.57 | 1.72 | 1.65 | 1.61 | 1.54 | 1.49 |
Communality refers to the proportion of variance in the biomarker accounted for by the seven factors at a given time point
Factor loadings (0.4 < |F| ≤ 1.0) denoted by light highlighting.
Color corresponds to the factor loading number at each time point (F1=blue, F2=Red, F3=Green, F4=Orange, F5-F7=Grey).