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. Author manuscript; available in PMC: 2022 Jul 15.
Published in final edited form as: AIDS. 2021 Jul 15;35(9):1395–1402. doi: 10.1097/QAD.0000000000002897

Table 2:

AT Density (HU) by Randomization Arm.

Tesamorelin Responders (N=193) Placebo (N=148) P value
Baseline*
 VAT density −91.2 (8.8) −91.4 (8.9) 0.80
 SAT density −94.1 (10.7) −95.3 (10.9) 0.29
26-week change*
 VAT density 6.2 (8.7) 0.3 (4.2) <0.001
 SAT density 4.0 (8.7) 0.3 (4.8) <0.001
Difference in 26-week change between Tesamorelin vs Placebo
Unadjusted 26-week change Estimated Slope 95%CI p-value
 VAT density (95% CI) 5.9 (4.5, 7.3) <0.001
 SAT density (95% CI) 3.7 (2.3, 5.2) <0.001
Adjusted 26-week change**
 VAT density (95% CI) 2.3 (0.9, 3.7) 0.001
 SAT density (95% CI) 3.5 (2.3, 4.7) <0.001
*

mean (standard deviation)

**

adjusted for baseline AT density, baseline AT area and change in AT area

HU effect size estimate and 95% confidence interval

AT=adipose tissue, VAT=visceral adipose tissue, SAT=subcutaneous adipose tissue, HU=Hounsfield Units