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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Ultrasound Med Biol. 2021 May 14;47(8):2193–2201. doi: 10.1016/j.ultrasmedbio.2021.03.039

Table 2.

Summary of the relationship between shear wave elastography parameters and IHC parameters.

SWE parameters Emean±SD
(kPa)
Emax±SD
(kPa)
Emin±SD
(kPa)
Esd±SD
(kPa)
fmass±SD
(Hz)
ER
P value 0.63 0.59 0.08 0.20 0.004*
 Negative (39) 73.4±36.6 153.3±64.9 26.6±23.6 2.7±1.9 166.0±78.2
 Positive (225) 76.6±37.7 149.4±65.2 31.4±23.0 2.4±1.7 230.1±132.1
PR
P value 0.48 0.77 0.10 0.24 0.001*
 Negative (50) 72.5±34.3 152.8±64.4 26.6±21.7 2.7±2.0 160.4±76.7
 Positive (214) 77.0±38.3 149.3±65.4 31.6±23.4 2.3±1.6 234.7±133.0
HER2
P value 0.67 0.004* 0.45 <0.001* <0.001*
 Negative (218) 79.0±37.9 151.2±62.9 32.5±24.2 2.3±1.6 235.1±129.4
 Positive (31) 79.1±22.8 184.6±45.6 25.7±13.1 3.6±2.1 130.4±66.4
Ki-67
P value 0.05 0.03* 0.21 0.12 <0.001*
 <14% (101) 74.5±38.0 144.5±62.9 30.5±22.4 2.2±1.5 262.4±128.9
 ≥14% (114) 83.6±36.0 162.5±62.3 34.8±24.8 2.6±1.9 206.6±128.0
IHC subtype
P value 0.01* <0.001* 0.01* 0.01* <0.001*
 Luminal A (99) 75.6±37.5 145.6±61.8 31.0±22.3 2.2±1.5 265.5±128.2
 Luminal B with HER2− (82) 84.1±38.8 156.1±65.7 36.4±25.8 2.4±1.7 227.8±138.4
 Luminal B with HER2+ (23) 83.5±21.8 192.9±39.4 27.6±13.1 3.6±2.0 127.6±59.6
 HER2+ (6) 64.6±24.8 162.2±65.4 18.8±13.7 3.9±2.8 125.8±87.9
 TN (23) 75.6±37.5 153.1±66.5 26.6±21.7 2.5±1.7 175.8±77.0

The numbers in parenthesis are the mass numbers. SD indicates standard deviation.

Abbreviations: IHC= immunohistochemical; ER=estrogen receptor status; PR=progesterone receptor; HER2=human epidermal growth factor receptor 2; TN=triple negative.

*

p<0.05, difference is statistically significant.