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. 2021 Mar 23;151(6):1561–1571. doi: 10.1093/jn/nxab042

TABLE 4.

Multivariable linear associations of %E as NOS from solid foods and drinks with cardiometabolic risk factors and in an adult sample (n = 1019) from the province of Quebec, Canada1

Model 12 Model 23 Model 34
β (95%CI) P β (95%CI) P β (95%CI) P
WC, cm
 %E NOS, solid foods –0.63 (–0.96, –0.29) 0.0002 –0.43 (–0.78, –0.08) 0.01 –0.22 (–0.50, 0.06) 0.13
 %E NOS, drinks 0.04 (–0.46, 0.54) 0.88 0.20 (–0.25, 0.64) 0.38 0.16 (–0.27, 0.59) 0.47
BMI , kg/m2
 %E NOS, solid foods –0.226 (–0.369, –0.083) 0.002 –0.152 (–0.298, –0.006) 0.04 –0.080 (–0.205, 0.045) 0.21
 %E NOS, drinks 0.037 (–0.162, 0.236) 0.71 0.088 (–0.083, 0.259) 0.31 0.076 (–0.090, 0.242) 0.37
Fasting glucose,5,6 %
 %E NOS, solid foods –0.061 (–0.268, 0.146) 0.56 0.057 (–0.128, 0.243) 0.55 0.026 (–0.182, 0.235) 0.81
 %E NOS, drinks –0.371 (–0.743, 0.003) 0.05 –0.360 (–0.742, 0.024) 0.07 –0.355 (–0.737, 0.029) 0.07
Fasting insulin,5,6 %
 %E NOS, solid foods –1.46 (–2.70, –0.20) 0.02 –0.67 (–1.70, 0.36) 0.20 –0.63 (–1.72, 0.49) 0.27
 %E NOS, drinks 1.78 (0.18, 3.41) 0.03 1.86 (0.36, 3.38) 0.02 1.84 (0.34, 3.36) 0.02
HOMA-IR,6 %
 %E NOS, solid foods –1.52 (–2.89, –0.13) 0.03 –0.62 (–1.73, 0.50) 0.28 –0.60 (–1.81, 0.62) 0.33
 %E NOS, drinks 1.40 (–0.31, 3.15) 0.11 1.49 (–0.13, 3.14) 0.07 1.48 (–0.14, 3.13) 0.07
CRP,5,6 %
 %E NOS, solid foods –3.09 (–4.77, –1.39) 0.0004 –1.43 (–2.94, 0.10) 0.07 –1.14 (–2.76, 0.52) 0.18
 %E NOS, drinks –0.10 (–3.51, 3.42) 0.95 1.42 (–1.62, 4.56) 0.36 1.34 (–1.68, 4.44) 0.39
TGs,5,6 %
 %E NOS, solid foods –1.91 (–3.71, –0.08) 0.04 –1.14 (–2.71, 0.44) 0.16 –0.95 (–2.56, 0.68) 0.25
 %E NOS, drinks –0.66 (–2.33, 1.04) 0.44 –0.33 (–1.91, 1.28) 0.69 –0.37 (–1.95, 1.23) 0.65
LDL-C5, mmol/L
 %E NOS, solid foods –0.010 (–0.025, 0.005) 0.17 –0.004 (–0.018, 0.011) 0.63 –0.003 (–0.017, 0.012) 0.72
 %E NOS, drinks –0.009 (–0.037, 0.020) 0.55 –0.006 (–0.036, 0.023) 0.68 –0.006 (–0.036, 0.023) 0.67
HDL-C,5 mmol/L
 %E NOS, solid foods 0.0083 (–0.0028, 0.0193) 0.14 0.0011 (–0.0079, 0.0101) 0.81 0.0003 (–0.0089, 0.0095) 0.95
 %E NOS, drinks –0.0101 (–0.0229, 0.0028) 0.12 –0.0107 (–0.0225, 0.0011) 0.08 –0.0105 (–0.0224, 0.0013) 0.08
TC:HDL-C,5 mmol/L
 %E NOS, solid foods –0.036 (–0.069, –0.003) 0.03 –0.016 (–0.044, 0.012) 0.25 –0.010 (–0.036, 0.016) 0.46
 %E NOS, drinks –0.013 (–0.056, 0.030) 0.55 –0.008 (–0.050, 0.033) 0.69 –0.010 (–0.051, 0.032) 0.65
SBP, mm Hg
 %E NOS, solid foods –0.12 (–0.38, 0.13) 0.35 0.09 (–0.17, 0.36) 0.50 0.10 (–0.19, 0.38) 0.50
 %E NOS, drinks 0.18 (–0.22, 0.57) 0.39 0.21 (–0.18, 0.60) 0.29 0.21 (–0.18, 0.61) 0.29
DBP, mm Hg
 %E NOS, solid foods –0.25 (–0.42, –0.09) 0.003 –0.11 (–0.27, 0.06) 0.21 –0.07 (–0.25, 0.12) 0.47
 %E NOS, drinks 0.21 (–0.07, 0.50) 0.13 0.22 (–0.04, 0.48) 0.10 0.21 (–0.05, 0.46) 0.12
MS z score7
 %E NOS, solid foods –0.106 (–0.189, –0.022) 0.01 –0.021 (–0.071, 0.029) 0.40 –0.014 (–0.064, 0.036) 0.59
 %E NOS, drinks –0.034 (–0.133, 0.064) 0.49 –0.005 (–0.074, 0.065) 0.89 –0.007 (–0.077, 0.063) 0.85
1

Values are estimates of the change in the outcome (95% CI) for every unit of %E NOS from solid foods or drinks. Individuals taking medication that could affect the studied outcome were removed from analyses. See the Methods section for details. n is listed for each variable: WC and BMI (n = 1017); fasting glucose, fasting insulin, and HOMA-IR (n = 963); CRP (n = 868); TGs, LDL-C, HDL-C, and TC:HDL-C (n = 911); SBP and DBP (n = 902); and MS z score (n = 816). AHEI, Alternative Healthy Eating Index–2010; CRP, C-reactive protein; DBP, diastolic blood pressure; HDL-C, HDL cholesterol; LDL-C, LDL cholesterol; MS z score, continuous metabolic syndrome risk score; NOS; naturally occurring sugar; SBP, systolic blood pressure; TC, total cholesterol; TG, triglyceride; WC, waist circumference; %E, percentage of daily energy.

2

Model 1 is adjusted for sex, age, and administrative region.

3

Model 2 is adjusted for model 1 + WC (except when WC or BMI is the studied outcome), educational and household income levels, smoking, physical activity [based on the 2005 International Physical Activity Questionnaire (IPAQ) categorical scoring rules], mean daily energy intake, plausibility of self-reported energy intake, and the number of 24-h dietary recalls completed on weekend days.

4

Model 3 is adjusted for model 2 + AHEI partial score (AHEI score from which whole fruits and sugar-sweetened beverages and fruit juice subscores were removed).

5

Blood tests were performed on serum.

6

Log-transformed data; β values (95% CI) are expressed as % change upon back-transformation calculated as 100 × exponential (logB) − 100.

7

A higher MS z score indicates a stronger presence of the metabolic syndrome.