TABLE 5.

HRs of incident atrial fibrillation according to baseline n–3 and n–6 PUFA concentrations (fourth compared with first quartile) in Multi-Ethnic Study of Atherosclerosis participants stratified by race/ethnicity¹

PUFA	White	Chinese American	Black	Hispanic	P-interaction
Phospholipid ALA
n cases/total	390/2422	105/779	171/1630	147/1398
HR (95% CI)	1.20 (0.87, 1.65)	1.22 (0.67, 2.23)	1.09 (0.69, 1.73)	1.09 (0.68, 1.75)	0.82
Phospholipid EPA
n cases/total	390/2422	105/779	171/1630	147/1398
HR (95% CI)	1.02 (0.74, 1.40)	1.11 (0.61, 2.03)	0.62 (0.39, 0.99)2	0.94 (0.55, 1.61)	0.031
Phospholipid n–3 DPA
n cases/total	390/2422	105/779	171/1630	147/1398
HR (95% CI)	0.81 (0.60, 1.09)	1.08 (0.63, 1.84)	0.86 (0.57, 1.30)	0.69 (0.41, 1.16)	0.10
Phospholipid n–3 DHA
n cases/total	390/2422	105/779	171/1630	147/1398
HR (95% CI)	1.02 (0.73, 1.41)	0.53 (0.18, 1.51)	0.47 (0.27, 0.79)3	0.52 (0.27, 0.98)2	0.016
Phospholipid LA
n cases/total	390/2422	105/779	171/1630	147/1398
HR (95% CI)	0.99 (0.72, 1.35)	0.70 (0.31, 1.59)	0.91 (0.52, 1.58)	1.04 (0.64, 1.69)	0.70
Phospholipid AA
n cases/total	390/2422	105/779	171/1630	147/1398
HR (95% CI)	0.90 (0.66, 1.22)	0.92 (0.47, 1.79)	0.59 (0.36, 0.97)2	0.71 (0.43, 1.20)	0.55

¹Cox proportional hazard model adjusted for age, sex, education, income, site, height, BMI, cigarette smoking, diabetes, blood pressure, antihypertensive medication, physical activity, and alcohol consumption. AA, arachidonic acid; ALA, α-linolenic acid; DPA, docosapentaenoic acid; LA, linoleic acid.

²0.01 < P < 0.05.

³0.001 < P < 0.01.