Table 1.

Expression Pattern of Bone‐Associated Genes and FcyR‐Associated Genes

	M‐CSF	M‐CSF RANKL	M‐CSF RANKL untreated IgG complex	M‐CSF RANKL de‐IgG complex
NFATc1	100 ± 12	401 ± 95***	424 ± 97***	395 ± 92***
CTSK	100 ± 57	238 ± 105*	324 ± 79***	427 ± 105 *** #
RANK	100 ± 12	141 ± 11**	135 ± 15**	131 ± 13 **
Fcgr1	100 ± 22	799 ± 350 ***	1020 ± 285 ***	1048 ± 278 ***
Fcgr3	100 ± 23	230 ± 73**	279 ± 125 ***	355 ± 80 **, #

Stimulation is presented as per cent of expression in M‐CSF stimulated cells, set to 100% ±SEM, n = 4, experiment repeated once with similar results.

M‐CSF; macrophage colony‐stimulating factor, RANKL; receptor activator of nuclear kappa‐B ligand, IgG; immunoglobulin G, de‐IgG; desialylated IgG

^* P < .05,

^** P < .01,

^*** P < .001 vs M‐CSF,

^# P < .05 vs M‐CSF + RANKL analysed using one‐way ANOVA followed by Tukey's comparison with all groups.