TABLE 1.
Paraben mix allergy frequencies reported by the largest contact dermatitis surveillance working groups in North America and Europe (1992 ‐ 2019).
| Test cycles | Percentage positivity rate (no. of patch‐tests) | |||||
|---|---|---|---|---|---|---|
| NACDG a | Mayo Clinic | ESSCAb | IVDKc | |||
| 1992 – 1993 | 2.3 (3 508)(24) | |||||
| 1993 – 1994 | ||||||
| 1994 – 1995 | 1.8 (3 086)(25) | |||||
| 1995 – 1996 | ||||||
| 1996 – 1997 | 1.7 (4 096)(28) | 1.3 (121 247)(53) | ||||
| 1997 – 1998 | ||||||
| 1998 – 1999 | 1.0 (5 803)(29) | 1.6 (1 318)(36) | ||||
| 1999 – 2000 | ||||||
| 2000 – 2001 | ||||||
| 2001 – 2002 | 0.6 (4 898)(30) | 1.7 (3 841)(37) | ||||
| 2002 – 2003 | 1.2 (8 857)(47) | |||||
| 2003 – 2004 | 1.1 (5 142)(31) | |||||
| 2004 – 2005 | 1.0 (9 166)(48) | |||||
| 2005 – 2006 | 1.2 (4 439)(32) | 1.0 (17 197)(49) | ||||
| 2006 – 2007 | 1.7 (3 090)(38) | |||||
| 2007 ‐ 2008 | 1.1 (5 082)(33) | 1.0 (23 331)(50) | 0.9 (43 029)(54) | |||
| 2008 – 2009 | ||||||
| 2009 – 2010 | 0.8 (4 304)(34) | 0.7 (52 586)(51) | ||||
| 2010 – 2011 | ||||||
| 2011 – 2012 | 1.4 (4 231)(35) | 0.8 (2 576)(39) | 0.6 (44 366)(54) | |||
| 2012 – 2013 | ||||||
| 2013 – 2014 | 0.6 (4 859)(26) | 0.5 (28 569)(52) | ||||
| 2014 – 2015 | ||||||
| 2015 – 2016 | 0.6 (5 593)(27) | 0.8 (36 983)(54) | ||||
| 2016 – 2017 | ||||||
| 2017 – 2018 | ||||||
| 2018 ‐ 2019 | ||||||
a
North American Contact Dermatitis Group.
b
European Surveillance System on Contact Allergies.
c
Information Network of Departments of Dermatology.