. 2020 Dec 1;155(5):748–754. doi: 10.1093/ajcp/aqaa185

Table 1.

List of Cases Examined, Comparing Cell of Origin Classification by Different Methods, and Reporting Mutations Detected by FusionPlex Lymphoma Panel by Case^a

Case	Age (y)/Sex	FPL	Hans	NS	Gene	Mutation	VAF, %
1	59 F	ABC	ABC	ABC
2	57 M	GCB	GCB	GCB
3	52 M	ABC	ABC	ABC	MYC	p.Gln52del	10.5
4	69 M	ABC	ABC	ABC
5	86 F	GCB	GCB	GCB	TNFRSF13B	p.Cys104Tyr	75.0
					BRAF	p.Lys601Glu	48.0
6	60 M	ABC	ABC	ABC	MYD88	p.Val217Phe	30.1
7	53 M	GCB	GCB	GCB	BLNK	p.Glu60Lys	38.1
8	75 M	GCB	GCB	GCB
9	76 F	ABC	ABC	ABC	TCF3	p.Gly362Asp	59.5
					ALK	p.Thr1026Pro	22.0
10	52 F	ABC	ABC	ABC	XPO1	p.Glu571Lys	31.8
11	31 M	GCB	GCB	GCB	MYC	p.Pro233Thr	89.7
12	83 M	GCB	GCB	GCB
13	34 M	GCB	GCB	GCB
14	44 F	ABC	ABC	ABC	KRAS	p.Gly12Cys	23.1
					AICDA	p.Arg25His	29.1
15	39 F	GCB	GCB	GCB
16	43 M	GCB	GCB	GCB	MYC	p.Asp2His	51.1
					SYNE1	p.Leu3057Val	52.5
17	60 M	ABC	ABC	ABC
18	27 F	GCB	GCB	GCB	XPO1	p.Glu571Lys	36.0
19	62 M	ABC	ABC	ABC	MUC1	p.Arg99Cys	49.1
20	74 F	GCB	GCB	GCB	BLNK	p.Gly30Arg	48.2
21	39 M	GCB	GCB	GCB
22	62 M	GCB	GCB	GCB	PIM1	p.Glu170Asp	41.5
					ALK	p.Thr1026Pro	37.1
23	84 F	GCB	GCB	GCB
24	61 M	ABC	ABC	ABC	BCL3	p.Ala68Val	48.8
25	70 M	GCB	GCB	GCB	BCL2	p.Pro233Thr	89.7
26	71 M	ABC	ABC	ABC	PIM1	p.Ala113Thr	74.2
					PIM1	p.Gly141Asp	73.8
					PIM1	p.Gly119Asp	47.8
					PIM1	p.Asn269Ser	18.5
					MYD88	p.Leu265Pro	33.8
27	61 F	GCB	GCB	GCB	PDCD1LG2	p.Glu11AsnfsTer7	66.7
28	35 M	GCB	ABC	GCB
29	65 F	GCB	ABC	GCB	ALK	p.Thr1026Pro	28.6
30	74 M	GCB	ABC	GCB	ALK	p.Thr1026Pro	25.8
31	72 F	UNC	ABC	UNC	TCF3	p.Gly362Asp	57.4
					KMT2A	p.Leu3614Pro	52.9
32	62 M	GCB	ABC	GCB	BCL2	p.Ser87Arg	25.2
33	21 M	GCB	ABC	GCB
34	66 M	UNC	ABC	UNC
35	84 F	GCB	ABC	ABC
36	42 M	UNC	ABC	ABC
37	31 M	GCB	ABC	ABC
38	71 M	ABC	ABC	GCB
39	59 M	GCB	ABC	ABC	ETV6	p.Lys11Asn	34.8
					MYD88	p.Leu265Pro	51.9
					ALK1	p.Thr1026Pro	53.3
40	66 M	GCB	GCB	UNC	BMP7	p.Pro106Ala	92.9
					PIM1	p.Val90Leu	51.8
					PIM1	p.Val90Ile	41.0
41	83 F	ABC	ABC	GCB	LRMP	p.Ile102Val	46.6

ABC, activated B-cell subtype; FPL, Archer FusionPlex Lymphoma assay; GCB, germinal center B-cell subtype; NS, NanoString; UNC, unclassified; VAF, variant allele fraction.

^aFor the purposes of comparison between methods, cases classified as ABC and UNC categories by the FusionPlex Lymphoma panel and/or NS were considered non-GCB.