Table 2.

Overview of BCL2, BCL6, and MYC Translocations Detected by Various Methods

Case	Gene	Partner Gene	COO (FPL)	Detected by FPL	Detected by CG	Detected by FISH
1	BCL6	IGH	ABC	N	Y	Y
2	BCL6	UD	GCB	N	Y	—
3Aa	BCL6	IGH	ABC	Y	N	Y
3B	BCL2	UD	ABC	N	Y	—
4a	BCL6	IGH	ABC	Y	N	Y
6	MYC	IGH	ABC	Y	Y	—
10	BCL6	IGH	ABC	Y	—	Y
11a	MYC	IGH	GCB	Y	N	Y
14	BCL6	IGH	ABC	Y	N	N
16	MYC	UD	GCB	N	Y	Y
17A	BCL6	IGH	ABC	Y	Y	Y
17B	MYC	UD	ABC	N	Y	Y
28	BCL2	IGH	GCB	Y	—	Y
30A	BCL2	IGH	GCB	Y	Y	—
30B	BCL6	UD	GCB	N	Y	—
32	BCL6	UD	GCB	N	Y	Y
34a	BCL6	RCC1	UNC	Y	N	Y
37	BCL6	UD	GCB	N	Y	Y

ABC, activated B-cell subtype; CG, cytogenetics; COO, cell of origin (by FusionPlex Lymphoma assay); FISH, fluorescence in situ hybridization; FPL, FusionPlex Lymphoma assay; GCB, germinal center B-cell subtype; N, no; UD, undetermined; UNC, unclassified; Y, yes; —, test not performed.

^aTranslocations detected by FPL and missed by CG.