Table 4.
Comparison of the diagnostic efficiency between initial trophectoderm and noninvasive preimplantation genetic testing for aneuploidy with the corresponding inner cell mass result as the true result.
Performance characteristic | Initial TE (n = 26), n (%) | niPGT-A (n = 26), n (%) | P value |
---|---|---|---|
False-positive rate | 3/3 (100) | 0/3 (0) | .100 |
False-negative rate | 0/23 (0) | 0/23 (0) | − |
Sensitivity | 23/23 (100) | 23/23 (100) | − |
Specificity | 0/3 (0) | 3/3 (100) | .100 |
Accuracy | 23/26 (88.5) | 26/26 (100) | .235 |
Positive predictive value | 23/26 (88.5) | 23/23 (100) | .237 |
Negative predictive value | − | 3/3 (100) | − |
Note: ICM = inner cell mass; niPGT-A = noninvasive preimplantation genetic testing for aneuploidy; TE = trophectoderm.