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The inter-domain linker region after the conserved G580 residue adopts a different conformation in EcLon than in YpLon and MtLon. (A) Alignment based on the α domain of EcLon with YpLon (PDB: 6ON2) (both residues marked in black are identical in type and sequence number). (B) An analogous alignment of EcLon with MtLon (PDB: 4YPL) (residues of interest color coded). All figures made with Chimera (Pettersen et al., 2004) and Chimera X (Goddard et al., 2018).
