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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Dev Rev. 2021 Jun 8;61:100968. doi: 10.1016/j.dr.2021.100968

Figure 1. Scheme of the Hypothalamic-Pituitary-Adrenal (HPA) Axis.

Figure 1

Note. Activating pathways are indicated by solid lines, inhibitory – with dashed ones; circular sector icons represent receptors. ACTH – adrenocorticotropic hormone, CRH – corticotropin-releasing hormone, CRHBP – corticosterone-releasing hormone binding protein, CRHR – corticotropin-releasing factor receptor, FKBP5 – FK506-binding protein 51, GR – glucocorticoid receptor, MC2R – melanocortin-2 receptor, and MR – mineralocorticoid receptor.