Table 2.
Cycle characteristics and birth outcomes.
| Variable | PCOS (n = 64) | Control (n = 64) | P value | PCOS-HA (n = 47) | Control (n = 47) | P value | PCOS-NA (n = 17) | Control (n = 17) | P value |
|---|---|---|---|---|---|---|---|---|---|
| Total GND, mean (SE) | 2,990.4 (167.2) | 3,673.0 (166.7) | .014 | 2,805.5 (196.5) | 3,644.1 (195.7) | .01 | 3,489.9 (303.2) | 3,748.6 (303.1) | .59 |
| Days stim, mean (SE) | 9.85 (0.19) | 9.65 (0.19) | .49 | 9.65 (0.24) | 9.69 (0.24) | .91 | 10.4 (0.33) | 9.6 (0.32) | .15 |
| Peak E2, mean (SE) | 3,232.0 (185.7) | 2,413.74 (183.7) | .009 | 3,078.2 (210.9) | 2,498.2 (207.8) | .08 | 3,676.11 (387.3) | 2,230.31 (386.5) | .08 |
| Oocytes, mean (SE) | 22.14 (1.25) | 14.42 (1.24) | .0009 | 21.66 (1.4) | 14.49 (1.4) | .006 | 23.56 (2.7) | 14.23 (2.7) | .09 |
| % Mature, mean (SE) | 84.46 (1.79) | 81.7 (1.77) | .29 | 84.81 (2.1) | 80.78 (2.1) | .20 | 83.75 (3.5) | 84.83 (3.5) | .84 |
| Fert rate (%), mean (SE) | 79.68 (1.98) | 78.53 (1.95) | .68 | 81.56 (2.10) | 76.299 (2.07) | .11 | 74.68 (4.4) | 84.86 (4.3) | .20 |
| Blast rate (%), mean (SE) | 56.06 (2.89) | 51.07 (2.80) | .24 | 55.43 (3.4) | 49.31 (3.31) | .23 | 57.94 (5.6) | 56.03 (5.3) | .82 |
| FET, n (%) | 63 (90) | 59 (77) | .03 | 51 (88) | 39 (75) | .08 | 12 (100) | 20 (80) | .15 |
| eSET n (%)a |
61 (88) | 73 (95) | .23 | 53 (93) | 49 (94) | .99 | 8 (66.7) | 24 (96) | .04 |
| PGT-A, n (%) | 38 (60) | 41 (59) | .85 | 26 (54) | 27 (55) | .99 | 12 (80) | 14 (70) | .45 |
| Euploid rate (%), mean (SE) | 49 (4) | 48 (4) | .79 | 53 (5) | 44 (4) | .26 | 41 (8) | 55 (7) | .33 |
| Cardiac activity, n (%) | 37 (54.4) | 44 (57.1) | .75 | 30 (52.6) | 30 (58.8) | .54 | 7 (63.6) | 14 (53.9) | .57 |
| Live birth, n (%) | 32 (45.7) | 42 (53.9) | .33 | 26 (44.8) | 28 (54.9) | .33 | 6 (50.0) | 14 (51.9) | .97 |
| Miscarriage, n (%) | 21 (29.6) | 11 (14.1) | .018 | 16 (27.6) | 8 (15.7) | .14 | 5 (38.5) | 3 (11.3) | .07 |
Note: Blast = blastulation; eSET = elective single embyro transfer; E2 = estradiol; Fert = fertilization; FET = frozen embryo transfer; GND = gonadotropin; PGT-A = preimplantation genetic testing for aneuploidies; SE = standard error; stim = stimulated.
a
All embryo transfers that we were not eSET were double embryo transfers.