Table 3.
Baseline clinical characteristics and variables of the ECPR group and the CCPR group of studies included.
| Asystole, n (%) |
PEA, n (%) |
VF/VT, n (%) |
CPR duration (min) |
CPR to ECMO duration (min) |
ROSC (ROSB), n (%) |
Presume cardiac etiology, n (%) |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Authors, year, country | ECPR | CCPR | ECPR | CCPR | ECPR | CCPR | ECPR | CCPR | ECPR | CCPR | ECPR | CCPR | ECPR | CCPR |
| Chen et al. 200848 Taiwan | 13 (22) | 31 (27) | 17 (29) | 46 (41) | 29 (42) | 36 (32) | 53 ± 37 | 43 ± 31 | … | … | 55 (93) | 63 (56) | 59 (100) | 113 (100) |
| Kim et al. 201445 South Korea | 14 (26) | 268 (60) | 10 (18) | 91(21) | 31 (56) | 85 (19) | 62 (47–89) | 35 (21–50) | 1.5 (0.6–6.4)* | … | 44 (80) | 212 (48) | 49 (89) | 267 (62) |
| Maekawa et al. 201346 Japan | … | … | … | … | 32 (60) | 24 (22) | 49 (41–59) | 56 (47–66) | … | … | … | … | … | … |
| Sakamoto et al. 201447 Japan | … | … | … | … | 258 (100) | 193 (100) | … | … | … | … | … | … | 226 (87) | 150 (77) |
| Shin et al. 201349 South Korea | 10 (12) | 47 (15) | 50 (59) | 201 (63) | 25 (29) | 73 (23) | 42 ± 26 | 41 ± 37 | … | … | 64 (75) | 167 (52) | 63 (74) | 182 (57) |
| Siao et al. 201550 Taiwan | … | … | … | … | 20 (100) | 40 (100) | 70 ± 50 | 34 ± 18 | 49 ± 43.9 | … | 19 (95) | 19 (48) | 16 (80) | 21 (53) |
Abbreviations: CPR = cardiopulmonary resuscitation; CCPR = conventional cardiopulmonary resuscitation; ECLS = extracorporeal life support; ECPR = extracorporeal cardiopulmonary resuscitation; ECMO = extracorporeal membrane oxygenation; PEA = pulseless electrical activity; ROSB = return of spontaneous heartbeat; ROSC = return of spontaneous circulation; VF = ventricular fibrillation; VT = ventricular tachycardia.
Notes: Total percentages refer to studies with available data and continuous variables reported as mean ± SD or as median IQR.
Studies reporting in-hospital cardiac arrest did not report collapsed-time to CPR though it was considered to be minimal as per inclusion criteria.
CPR duration was defined as the interval between initiation of CPR and ROSC or death in the CCPR group, and as the interval between initiation of CPR and ECLS implantation in the ECPR group. Return of spontaneous heartbeat was identified by echocardiography in the ECPR group and by palpable central pulse or peripheral arterial pulse in the CCPR group.
*The median time interval from ROSC to ECPR implantation was 1.5 (range 0.6–6.4) hours.