Table 1. Intrahepatic disposition of Dox formulations (mean ± SD; n = 4).

Formulations	Hepatocytes(H) (μg)	NPC(μg)	H:NPC ratio	Fold enhancement in hepatocyte accumulationReference: Dox solution
1 h
Pul-AGn NPs	13.99 ± 0.24	1.78 ± 0.12	88.7:11.3	134.51
AGn NPs	7.08 ± 0.49	1.02 ± 0.10	87.4:12.6	68.07
Pul NPs	7.95 ± 0.16	1.16 ± 0.06	87.3:12.7	76.44
NPs	1.78 ± 0.17	0.814 ± 0.12	68.6:31.4	17.11
Dox solution	0.10 ± 0.02	0.154 ± 0.04	40.3:59.7	Reference
24 h
Pul-AGn NPs	2.38 ± 0.13	0.38 ± 0.06	86.2:13.8
AGn NPs	1.11 ± 0.10	0.18 ± 0.03	86:13.9
Pul NPs	1.71 ± 0.07	0.28 ± 0.03	85.9:14
NPs	1.09 ± 0.10	0.45 ± 0.08	70.8:29.2
Dox solution	Not detected	Not detected		Reference