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. 2021 May 25;13(13):995–1012. doi: 10.2217/epi-2021-0055

Figure 4. . Placenta-specific chromosome 14 miRNA cluster & chromosome 19 miRNA cluster.

Figure 4. 

(A & B) Expression versus absolute fold change plots for cluster miRNAs at baseMean >1. Pink = upregulated in first trimester at false discovery rate <0.05. Purple = upregulated in third trimester at FDR <0.05. Blue = similarly expressed with p ≥ 0.05. Point labels are the miRNA names minus the ‘hsa-miR-’ prefix. (A) C14MC miRNAs. (B) C19MC miRNAs. (C & D) Pathway enrichment analysis with experimentally confirmed targets of the similarly expressed or differentially expressed miRNAs in (C) C14MC or (D) C19MC.

C14MC: Chromosome 14 miRNA cluster; C19MC: Chromosome 19 miRNA cluster; D: Differentially expressed; S: Similarly expressed.