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. 2021 May 25;13(13):995–1012. doi: 10.2217/epi-2021-0055

Table 1. . Demographics and birth outcomes.

  First trimester Third trimester p-value
n 110 44  
Maternal age, years 37.7 (3.0) 37.3 (3.0) 0.65
Paternal age, years 39.5 (4.8) 38.6 (4.8) 0.30
Maternal race/ethnicity
Caucasian 106 (96.4%) 35 (79.6%) 0.002
Non-Hispanic 107 (97.3%) 35 (79.6%) <0.001
Paternal race/ethnicity
Caucasian 104 (94.6%) 37 (84.1%) 0.04
Non-Hispanic 107 (97.3%) 36 (81.8%) 0.001
Fetal race/ethnicity
Caucasian 103 (93.6%) 32 (72.7%) <0.001
Non-Hispanic 106 (96.4%) 33 (75.0%) <0.001
Fetal female sex 57 (51.8%) 18 (40.9%) 0.22
Maternal pre-pregnancy BMI, kg/m2 21.9 (3.4) 24.0 (4.7) 0.005
Maternal pre-existing medical conditions
Hypertension 0 (0%) 0 (0%) -
Diabetes 0 (0%) 0 (0%) -
Thyroid disorder 3 (2.7%) 6 (13.6%) 0.02
Pregnancy complications
Hypertension (not pre-existing) 0 (0%) 8 (18.2%) <0.001
Gestational diabetes 3 (2.7%) 1 (2.3%) 1.0
Placenta previa 0 (0%) 1 (2.3%) 0.49
Placental abruption 0 (0%) 0 (0%) -
Hypertension management in pregnancy
Anti-hypertensives 0 (0%) 3 (6.8%) 0.022
Any magnesium use (ante or postpartum) 0 (0%) 6 (13.6%) <0.001
Mode of delivery – cesarean section 33 (30%) 15 (34.1%) 0.74
Gestational age at delivery, days 276.3 (7.0) 276.5 (8.0) 0.43
Birth weight, g 3435.4 (463.6) 3473.1 (467.0) 0.7

Values shown as mean (standard deviation) or n (%). P-values were adjusted for fetal sex.