Figure 3.

Time course of ∆SBP (A), ∆MAP(B), and ∆HR (C) after microinjection of saline, glutamate, GYK the non-NMDA antagonist of glutamate receptor, and co-injection of GYK and Glu into vlPAG nucleus in hemorrhagic condition. Data were expressed as mean±SEM; n= 6 (repeated measures ANOVA). ∆MAP: Mean arterial pressure, ∆SBP: Systolic blood pressure, ∆HR: Heart rate, vehicle: saline microinjection, Glu: glutamate, GYK: GYKI-52466. Differences with P-value <0.05 were considered significant. ***: P<0.001, **: P<0.01, and *: P<0.05 vs vehicle group, ###: P<0.001, ##: P<0.01, and #: P<0.05 vs Hem+saline group and ^^^: P<0.001, ^^: P<0.01, and ^: P<0.05 vs Glu group