Figure 4.

Time course of ∆SBP (A), ∆MAP(B), and ∆HR (C), after microinjection of the saline, glutamate, MK the NMDA antagonist of glutamate receptor, and co-injection of MK and Glu into vlPAG nucleus in hemorrhagic condition. Data were expressed as mean±SEM; n= 6 (repeated measures ANOVA). ∆MAP: mean arterial pressure, ∆SBP: systolic blood pressure, ∆HR: heart rate, vehicle: saline microinjection, Glu: glutamate, GYK: GYKI-52466, MK: MK801. Differences with P-value <0.05 were considered significant. ***: P<0.001, **: P<0.01, and *: P<0.05 vs vehicle group, ###: P<0.001, ##: P<0.01, and #: P<0.05 vs Hem+saline group and ^^^: P<0.001, ^^: P<0.01, and ^: P<0.05 vs Glu group