Figure 2.

SIRT3 activates the activity of antioxidant enzymes in the kidneys. (A) Immunohistochemical detection of iNOS protein expression in the kidney (×400). (B) Quantitative analysis of iNOS protein expression. (C) Expression levels of SOD in the kidney. (D) Expression level of CAT in the kidney. SIRT3, Sirtuin3; iNOS, inducible nitric oxide synthase; SOD, superoxide dismutase; CAT, catalase. Compared with WT-Sham group, ***P<0.001; compared with KO-Sham group, P<0.001; compared with WT-CLP group^{, ##}P<0.01, ^###P<0.001