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. 2021 Jun 24;8:645–656. doi: 10.2147/JHC.S312921

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© 2021 Lin et al.

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MR imaging with DOTA(Gd)-ANADYWR and Gd-EOB-DTPA in a DEN-induced HCC mouse. (A) Representative MR images and corresponding rainbow pseudo color images obtained before and at 5, 25 min after injection with DOTA(Gd)-ANADYWR or Gd-EOB-DTPA in a DEN-induced HCC mouse bearing an HCC lesion. (B) The corresponding gross photograph of the same lesion shown in (A) (The red arrowheads indicated the HCC. The red dotted circles indicated the visible HCC). (C) Integrin α6 expression was analyzed using immunohistochemistry IHC in tumor tissue (Scale bar, 50μm).