Table 1.
Demographic characteristics, HLA-DR status, serum MOG-IgG and AQP4-IgG positivity according to EBV serostatus.
| EBV-VCA IgG negative N=25 | EBV-VCA IgG positive N=164 | p-value$ | |
|---|---|---|---|
| Age at first presentation, median (IQR), y | 6.7 (4.4–10.8) | 14.6 (12.5, 16.0) | <0.001 |
| Female, n (%) | 17 (68%) | 111 (67.7%) | 1.00 |
| Race, n (%) | 0.20 | ||
| White | 14 (56%) | 110 (67.1%) | |
| Black | 1 (4%) | 16 (9.8%) | |
| Asian | 4 (16%) | 15 (9.2%) | |
| Mixed | 5 (20%) | 20 (12.2%) | |
| Unknown | 1 (4%) | 1 (0.6%) | |
| Pacific Islander | 0 | 2 (1.2%) | |
| Ethnicity, n (%) | 0.003 | ||
| Hispanic | 5 (20%) | 77 (47.0%) | |
| Non-Hispanic | 19 (76%) | 87 (53.0%) | |
| Unknown | 1 (4%) | 0 | |
| Positive for DRB1*15:01 or 15:03 | 4 (16%) | 64 (39.0%) | 0.019 |
| MOG-IgG positive | 11 (44%) | 9 (5.5%) | <0.001 |
| AQP4-IgG positive | 0 | 0 | NA |
$
Fisher’s exact test for categorical variables and Wilcoxon rank-sum test for continuous variables.