Table 1.

Characteristics of HDs, CHB, HBV-LC, and HBV-HCC patients

Variables	HDs	CHB	HBV-LC	HBV-HCC	P values
Case	32	23	25	133	NA
Age(years)	55.6 ± 12.8	35.9 ± 5.6*	55.1 ± 12.6	58.3 ± 11.4	<0.001
Gender(male/female)	17/15	14/9	15/10	103/30	0.09
HBVDNA(<100/≥100IU/ml)	NA	16/7	22/3	104/29	0.29
HBeAg(-/+)	NA	17/6	19/6	108/25	0.65
ALT(U/L)	26.7 ± 9.8	42.4 ± 16.8	33.3 ± 13.4	37.9 ± 40.2	0.26

Abbreviations: NA not applicable, HDs healthy donors, CHB chronic hepatitis B, HBV-LC hepatitis B virus-related liver cirrhosis, HBV-HCC HBV-related hepatocellular carcinoma, ALT aspartate aminotransferase

*p value < 0.05 vs HDs, HBV-LC or HBV-HCC group