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. Author manuscript; available in PMC: 2022 Apr 8.
Published in final edited form as: Brain Behav Evol. 2021 Apr 8;95(5):247–255. doi: 10.1159/000514858

Figure 1.

Figure 1.

Amphetamine-induced behaviors decrease after multiple exposures to the drug. Animals were immerged in a solution containing control (open squares) or control and 0.5 mM amphetamine (AMPH, open circles) for 10 minutes. The percentage of animals exhibiting swimming induced paralysis (SWIP) are reported on the Y axis. While no change in the percentage of animals exhibiting SWIP was observed between the first and second exposures to AMPH (A-B), a strong reduction was observed during the third (p < 0.001) and fourth (p < 0.001) exposures (C-D) with respect to the first exposure (2-way ANOVA test). N represents the number of animals tested per each group.