Table 2.
Self-reported and clinician-evaluated signs and symptoms associated with anxiety or depression (demographic data adjusted).
| Anxiety | Depression | |||
|---|---|---|---|---|
| Crude OR (95%CI) | Adjusted OR (95%CI) | Crude OR (95%CI) | Adjusted OR (95%CI) | |
| Self-reported signs and symptoms | ||||
| Flush duration | 0.995 (0.809–1.223) |
1.011 (0.820–1.247) |
0.882 (0.716–1.086) |
0.891 (0.721–1.100) |
| Flush times in the past 24 h | 1.110*
(1.003–1.229) |
1.122*
(1.011–1.245) |
1.213*
(1.091–1.349) |
1.223**
(1.098–1.362) |
| Flush frequency | 0.959 (0.830–1.109) |
0.959 (0.826–1.113) |
0.980 (0.846–1.134) |
0.976 (0.840–1.134) |
| Severity of flushing | 1.634**
(1.377–1.940) |
1.639**
(1.375–1.954) |
1.694**
(1.423–2.017) |
1.722**
(1.439–2.060) |
| Flushing–induced sleep disorders | 1.736**
(1.460–2.064) |
1.817**
(1.516–2.178) |
1.946**
(1.616–2.344) |
2.057**
(1.693–2.499) |
| Flushing–induced life distress | 1.908**
(1.608–2.265) |
1.892**
(1.589–2.252) |
1.892**
(1.595–2.246) |
1.909**
(1.601–2.275) |
| Severity of burning | 1.539**
(1.327–1.786) |
1.550**
(1.329–1.807) |
1.545**
(1.330–1.796) |
1.576**
(1.349–1.841) |
| Severity of stinging | 1.565**
(1.347–1.817) |
1.585**
(1.359–1.849) |
1.603**
(1.375–1.868) |
1.639**
(1.399–1.919) |
| Severity of itching | 1.429**
(1.235–1.653) |
1.450**
(1.248–1.685) |
1.494**
(1.287–1.735) |
1.539**
(1.318–1.796) |
| Severity of erythema | 1.211*
(1.031–1.423) |
1.241*
(1.051–1.465) |
1.212*
(1.031–1.425) |
1.249**
(1.057–1.477) |
| Clinicians-evaluated signs and symptoms | ||||
| Severity of erythema | 0.956 (0.807–1.132) |
0.977 (0.820–1.165) |
0.860 (0.724–1.021) |
0.878 (0.736–1.049) |
| Severity of papulopustule | 0.900 (0.794–1.019) |
0.884 (0.778–1.004) |
0.889 (0.784–1.008) |
0.866*
(0.761–0.985) |
| Severity of phymatous | 0.914 (0.758–1.103) |
0.927 (0.765–1.123) |
0.963 (0.796–1.164) |
0.982 (0.808–1.192) |
| Severity of telangiectasis | 1.201 (0.974–1.479) |
1.297*
(1.044–1.611) |
1.134 (0.918–1.400) |
1.213 (0.975–1.509) |
| Severity of plaque | 1.250 (0.906–1.724) |
1.286 (0.925–1.786) |
1.162 (0.841–1.605) |
1.197 (0.860–1.666) |
| Severity of swell | 1.377*
(1.063–1.785) |
1.507**
(1.148–1.978) |
1.187 (0.921–1.532) |
1.300 (0.996–1.696) |
*
p < 0.05;
**
p < 0.01; CI, confidence interval; OR, odds ratio.