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. 2021 May 31;113(11):1495–1505. doi: 10.1093/jnci/djab100

Table 4.

Intent-to-treat analysis of main effects: FCRI total score at T2 (week 8)

Component No. Estimated least squares mean
Estimateda T2-T0 difference (95% CI) Difference of estimated differences (95% CI) Effect size T2-T0 difference (95% CI) Difference of estimated effect sizes P b
T0 T1 T2
Relaxation
 Yes 98 54.5 48.8 42.8 −11.62 (−14.22 to −9.02) −1.69 (−5.39 to 2.01) −0.67 (−0.82 to −0.52) −0.10 (−0.31 to 0.12) .37
 No 98 51.7 45.1 41.8 −9.93 (−12.57 to −7.29) −0.57 (−0.72 to −0.42)
Worry practice
 Yes 99 53.3 48.0 43.8 −9.51 (−12.18 to −6.85) 2.52 (−1.18 to 6.22) −0.55 (−0.70 to −0.39) 0.14 (−0.07 to 0.36) .18
 No 97 52.9 45.9 40.8 −12.03 (−14.61 to −9.45) −0.69 (−0.84 to −0.54)
Cognitive restructuring
 Yes 98 53.3 48.1 43.7 −9.69 (−12.43 to −6.95) 2.17 (−1.55 to 5.89) −0.56 (−0.72 to −0.40) 0.12 (−0.09 to 0.34) .25
 No 98 52.8 45.8 41.0 −11.86 (−14.36 to −9.35) −0.68 (−0.83 to −0.54)
Telecoaching
 Yes 97 52.8 45.7 41.2 −11.55 (−14.12 to −8.98) −1.56 (−5.26 to 2.14) −0.66 (−0.81 to −0.52) −0.09 (−0.30 to 0.12) .41
 No 99 53.4 48.1 43.4 9.99 (−12.66 to −7.32) −0.58 (−0.73 to −0.42)
a

Estimated as least squares means from mixed model containing time (T0, T1, T2) and treatment condition (relaxation, worry practice, cognitive restructuring, telecoaching) and first-order time × treatment condition interaction terms. CI = confidence interval; FCRI = Fear of Cancer Recurrence Inventory; T0 = baseline; T1 = 4 weeks; T2 = 8 weeks.

b

P value from 2-sided t test of linear contrast of least squares means.