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. 2021 Jun 30;16(6):e0252966. doi: 10.1371/journal.pone.0252966

Table 3. Variable flip angle (VFA) measurement protocols.

T1—VFA Series GE Medical Systems Philips Siemens
Sequence 3D/FSPGR 3D/SPGR 3D/RF spoiled GRE
Scan Plane COR COR COR
Scan Options EDR/Z2 3D FFE; Fast = none
Section Thickness/Gap (mm) 3/0 6/0 6/0 (or 3/0 if error)
TR (ms) Min (6.0) 6.6 6.6
TE (ms) Min (1.4) 1.8 2.44
TI Values (ms)
Flip Angle (deg) 2, 5, 10, 20, 25, 30 2, 5, 10, 20, 25, 30 2, 5, 10, 20, 25, 30
ETL (Echo Train Length) 1 1 1
Number of Averages 4 4 4
Matrix (Frequency Encode) 256 256 256
Matrix (Phase Encode) 192 192 192
Matrix (Slice Encode)/# of Slices 34 28 32
Pixel Bandwidth (Hz) 488 904 280
Bandwidth (kHz)–GE only 62.5
FOV (FE, mm) 250 250 250
FOV (PE, mm) 250 250 250
Pixel Size (mm x mm) 0.98 x 0.98 0.98 x 0.98 0.98 x 0.98
Phase Encode Direction RL RL RL
User CVs Turbo = 0
Notes 1) Yields 30 3-mm sections.
2) Autoprescan with FA = 15.
3) Ensure gain settings do not vary between series, i.e., use Manual Prescan.
4) Include fiducial spheres above & below T1 spheres in scan volume.
5) Using Turbo = 0 should maintain the same TE/TR for each FA.
1) Reconstructed at 3 mm.
2) Ensure gain settings do not vary between series, i.e., use MPS.
Autoprescan using 15 deg FA.
3) Include fiducial spheres above & below T1 spheres in scan volume.
1) Reconstructed at 3 mm.
2) Ensure gain settings do not vary between series, i.e., use MPS.
Autoprescan using 15 deg FA.
3) Include fiducial spheres above & below T1 spheres in scan volume.
Series T1 VFA T1 VFA T1 VFA
Approximate Acquisition Time per Flip Angle Setting (min) 2.6 3.0 1.23
# of Flip Angle Settings 7 7 7
Total Time for this Series (min) 18.2 21.0 8.61