Table 4. Resistance profiles of the different Enterobacteriaceae isolated on admission and during hospitalization.
Enterobacteriaceae species (No.; %) n = 313 | No. (%) of resistant isolates at admission | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
AMX | AMC | FOX | CTX/CAZ | GN | AK | NA | NOR/CIP | SXT | ETP | |
E. coli (n = 152; 48) | 88 | 65 | 36 | 56 | 51 | 2 | 53 | 46 | 38 | 18 |
K. pneumoniae (n = 124; 39.6) | 124 | 80 | 3 | 79 | 72 | 0 | 39 | 39 | 49 | 17 |
E. cloacae (n = 11; 3.5) | * | * | * | 9 | 7 | 0 | 7 | 5 | 6 | 4 |
K. oxytoca (n = 10; 3.1) | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
C. freundii (n = 5; 1.5) | * | * | * | 3 | 2 | 1 | 2 | 2 | 1 | 0 |
P. mirabilis (n = 5; 1.5) | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
M. morganii (n = 2; 0.6) | * | * | * | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
C. braakii (n = 1; 0.3) | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
P. vulgaris (n = 1; 0.3) | * | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
P. stuartii (n = 1; 0.3) | * | * | * | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
S. marcescens (n = 1; 0.3) | * | * | * | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Enterobacteriaceae species (No.; %) n = 313 | 236 (75.3) | 169 (53.9) | 62 (19.8) | 149 (47.6) | 133 (42.4) | 3 (0.9) | 102 (32.5) | 93 (29.7) | 95 (30.3) | 40 (12.7) |
No. (%) of resistant isolates during NICU stay | ||||||||||
AMX | AMC | FOX | CTX/ CAZ | GN | AK | NA | NOR/CIP | SXT | ETP | |
K. pneumoniae (n = 195; 59.4) | 195 | 184 | 10 | 184 | 169 | 0 | 95 | 90 | 99 | 18 |
E. coli (n = 109; 33.2) | 100 | 96 | 63 | 93 | 89 | 9 | 79 | 77 | 28 | 26 |
E. cloacae (n = 6; 1.8) | * | * | * | 6 | 3 | 1 | 3 | 3 | 3 | 2 |
K. oxytoca (n = 6; 1.8) | * | 5 | 1 | 5 | 5 | 0 | 2 | 2 | 3 | 2 |
C. freundii (n = 5; 1.5) | * | * | * | 4 | 3 | 0 | 1 | 1 | 0 | 1 |
p. mirabilis (n = 4; 1.2) | 4 | 3 | 0 | 2 | 2 | 0 | 2 | 0 | 0 | 0 |
M. morganii (n = 2; 0.6) | * | * | * | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
E. aerogenes (n = 1; 0.3) | * | * | * | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Enterobacteriaceae species (No.; %) n = 328 | 319 (97.2) | 302 (92) | 88 (26.8) | 295 (89.9) | 272 (82.9) | 10 (3) | 182 (55.4) | 173 (52.7) | 133 (40.5) | 49 (14.9) |
*Natural resistance
AMP: ampicillin; AMC: amoxicillin / clavulanic acid; FOX: cefoxitin; CTX: cefotaxim; CAZ: ceftazidim; GN: gentamicin; AK: amikacin; NA: nalidixic acid; NOR: norfloxacin; CIP: ciprofloxacin, SXT: cotrimoxazol; ETP: ertapenem.