Table 4:
LAR | APR | MOR | |||||||
---|---|---|---|---|---|---|---|---|---|
| |||||||||
Outcome | SC-TNT n = 114 |
CRT n=144 |
p-value | SC-TNT n = 32 |
CRT n = 94 |
p-value | SC-TNT n = 10 |
CRT n = 21 |
p-value |
| |||||||||
Perioperative
Outcomes
| |||||||||
Any Complication (%) | 37 (32.5) | 45 (31.3) | 0.84 | 17 (53.1) | 36 (38.3) | 0.14 | 8 (80.0) | 16 (76.2) | 0.81 |
Severe Complication (%) | 8 (7.0) | 8 (5.6) | 0.63 | 5 (15.6) | 16 (17.0) | 0.85 | 2 (20.0) | 7 (33.3) | 0.44 |
Reoperation (%) | 3 (2.6) | 4 (2.8) | 0.94 | 1 (3.1) | 5 (5.3) | 0.61 | 1 (10.0) | 4 (20.0) | 0.49 |
Operative Time (mean min.±SD) | 205±60 | 212±61 | 0.32 | 229±60 | 247±96 | 0.33 | 262±108 | 359±146 | 0.07 |
Intra-Operative Complication (%) | 5 (4.4) | 7 (4.9) | 0.86 | 2 (6.3) | 5 (5.3) | 0.84 | 0 (0) | 1 (4.8) | 0.48 |
EBL (mean mL±SD) | 304±343 | 282±217 | 0.61 | 356±193 | 407±623 | 0.49 | 689±5 | 1,154± 1,102 |
0.13 |
Tumor Height | |||||||||
0 – 5 cm | 11 (9.7) | 39 (27.1) | <0.001* | 29 (90.6) | 84 (89.4) | 0.70 | 7 (70.0) | 13 (61.9) | 0.21 |
6 – 10 cm | 91 (79.8) | 76 (52.8) | 3 (9.4) | 8 (8.5) | 1 (10.0) | 7 (33.3) | |||
11 – 15 cm | 12 (10.5) | 29 (20.1) | 0 (0) | 2 (2.1) | 2 (20.0) | 1 (4.8) | |||
Diverting Ostomy | 111 (99.1) | 142 (98.6) | 0.91 | 4 (100.0) | 7 (100.0) | 1.00 | |||
30-d Mortality (%) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | |||
Length of Stay (mean days±SD) | 6.3±3.8 | 6.1±4.5 | 0.74 | 6.4±3.4 | 7.1±5.3 | 0.43 | 8.8±7.3 | 13.2±14.1 | 0.26 |
Quality of Resection | |||||||||
TME Complete (%) | 110 (96.5) | 137 (95.1) | 0.59 | 29 (90.6) | 88 (93.6) | 0.57 | 9 (90) | 17 (85) | 0.70 |
Negative Radial Margin (%) | 113 (99.1) | 141 (98.6) | 0.70 | 32 (100) | 89 (94.7) | 0.18 | 8 (88.9) | 17 (89.5) | 0.96 |
Negative Distal Margin (%) | 114 (100) | 139 (96.5) | 0.04* | 32 (100) | 93 (98.9) | 0.56 | 10 (100) | 21 (100) | 1.00 |
Legend: denotes significance; min=minutes; SD=Standard Deviation; LAR=Low Anterior Resection; APR=Abdominoperineal Resection; MOR=Multiorgan Resection; EBL=Estimated Blood Loss; TME=Total Mesorectal Excision. Reported rates of diverting ostomy in the MOR group correspond to the proportion of sphincter-sparing procedures