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. 2021 Jun 30;7(27):eabh3032. doi: 10.1126/sciadv.abh3032

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Fig. 5 — The black boxes indicate key proteins in SIP network, and those targeted by the five drugs are highlighted in red color. Sulfasalazine and proguanil target proteins in both pathways that directly and indirectly (via NADP production) affect NO production (58–61).