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. 2021 Jun 30;10:e66582. doi: 10.7554/eLife.66582

Figure 5. Calcineurin-NFAT signalling pathway in response to TAC after 2 days in WT and Trpm4 cKO mouse hearts.

(A) Representative western blots showing the expression of key proteins in the calcineurin-NFAT signalling pathway in cytoplasm (left) and nucleus (right). (B) Cytoplasmic (left) and nuclear (right) quantitative data were normalised by GAPDH and Histone H2B, respectively. Fold changes and cytoplasmic/nuclear ratios were calculated relative to sham groups, in each genotype. Results are presented as means ± SEM, n = 5–6/group, *p<0.05, **p<0.01.

Figure 5—source data 1. Source data file (Excel) for Figure 5B.

Figure 5.

Figure 5—figure supplement 1. Cytoplasmic/nuclear ratio of the key proteins in calcineurin-NFAT signalling pathway.

Figure 5—figure supplement 1.

Cytoplasmic/nuclear ratios are shown as fold changes relative to sham groups, in each genotype. Results are presented as means ± SEM, n = 6/group.
Figure 5—figure supplement 1—source data 1. Source data file (Excel) for Figure 5—figure supplement 1.