Comparison 2. Cilostazol 100 mg twice daily versus pentoxifylline 400 mg three times daily.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
2.1 Initial claudication distance (ICD)	1	417	Mean Difference (IV, Fixed, 95% CI)	20.00 [‐2.57, 42.57]
2.2 Absolute claudication distance (ACD)	2	866	Mean Difference (IV, Random, 95% CI)	13.43 [‐43.50, 70.36]
2.3 Adverse event related to study medication ‐ headache	2	982	Odds Ratio (M‐H, Random, 95% CI)	2.20 [1.16, 4.17]
2.4 Adverse event related to study medication ‐ diarrhoea	2	982	Odds Ratio (M‐H, Random, 95% CI)	1.80 [0.79, 4.12]
2.5 Adverse event related to study medication ‐ abnormal stools	1	459	Odds Ratio (M‐H, Fixed, 95% CI)	3.12 [1.57, 6.21]
2.6 Adverse event related to study medication ‐ pain	2	982	Odds Ratio (M‐H, Fixed, 95% CI)	0.85 [0.57, 1.26]
2.7 Adverse event related to study medication ‐ palpitations	2	982	Odds Ratio (M‐H, Fixed, 95% CI)	8.35 [4.11, 16.98]
2.8 All‐cause mortality	3	1229	Odds Ratio (M‐H, Fixed, 95% CI)	0.58 [0.17, 1.98]
2.9 Ankle brachial index (ABI)	1	417	Mean Difference (IV, Fixed, 95% CI)	‐0.01 [‐0.12, 0.10]