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. 2021 Jul 1;131(13):e148517. doi: 10.1172/JCI148517

Figure 5. scRNA-Seq identifies a distinct nasal epithelial cell subset in which SARS-CoV-2 is massively replicated in patients with COVID-19.

Figure 5

(A) Normalized mRNA expression level of SARS-CoV-2 nucleocapsid (N) in total clustered epithelial cells projected on UMAP plot. (B) List and proportion plots showing proportion of each epithelial cell subset in total SARS-CoV-2 N+ cells (left) and proportion of SARS-CoV-2 N+ cells within each cluster (right). (C) Violin plots depicting normalized mRNA expression levels of indicated SARS-CoV-2 genes in each cluster. (D) Normalized mRNA expression levels of indicated SARS-CoV-2 genes in total clustered epithelial cells projected on UMAP plot. (E) Comparison of proportion of SARS-CoV-2 genes among total detected genes per cell in each cluster. (F) List and proportion plots showing average percentages of SARS-CoV-2 genes in each cluster.