. 2021 Jun 30;32(7):79. doi: 10.1007/s10856-021-06539-1

Table 1.

Clinical and demographic data

	Groups				Total
Variable	EG		CG		p value
	n	%	n	%	n	%
Total	20	100.0	19	100.0	39	100.0	–
Gender							p⁽¹⁾ = 0,798
Male	6	30.0	5	26.3	11	28.2
Female	14	70.0	14	73.7	28	71.8
Age							p⁽²⁾ = 0.598
mean ± SD	61.50 ± 8.36		63.37 ± 12.92		62.41 ± 10.72
Age
range (years)							p⁽³⁾ = 0.074*
From 44 to 55	5	25.0	7	36.8	12	30.8
From 56 to 65	11	55.0	3	15.8	14	35.9
From 66 to 75	2	10.0	5	26.3	7	17.9
From 76 to 81	2	10.0	4	21.1	6	15.4
Comorbidities
Diabetes	2	10.0	4	21.1	6	15.4	p⁽³⁾ = 0.407
Hypertension	14	70.0	11	57.9	25	64.1	p⁽¹⁾ = 0.431
Benign breast lump	1	5.0	–	–	1	2.6	p⁽³⁾ = 1.000
Cardiopathy (CHF, Arrhythmia, CAD)	4	20.0	3	15.8	7	17.9	p⁽³⁾ = 1.000
Gastritis	1	5.0	–	–	1	2.6	p⁽³⁾ = 1.000
Asthma	1	5.0	–	–	1	2.6	p⁽³⁾ = 1.000
Erysipelas	3	15.0	1	5.3	4	10.3	p⁽³⁾ = 0.605
Gastric/breast neoplasm	2	10.0	–	–	2	5.1	p⁽³⁾ = 0.487
CVA	–	–	1	5.3	1	2.6	p⁽³⁾ = 0.487
Medications in use
Use of antihypertensive drugs	14	70.0	10	52.6	24	61.5	p⁽²⁾ = 0.265
Use of oral hypoglyceMIc agent	2	10.0	4	21.1	6	15.4	p⁽¹⁾ = 0.407
Insulin use	1	5.0	–	–	1	2.6	p⁽¹⁾ = 1.000
Symptomatic for CVI**	3	15.0	5	26.3	8	20.5	p⁽³⁾ = 0,451

*n = number of patients with Chronic Venous Ulcer (CVU)

EG experimental group using bacterial cemiulose, gel and film associated, CG control group, SD standard deviation, CHF congestive heart failure, CAD coronary artery disease, CVA cerebrovascular accident, CVI chronic venous insufficiency

**Diosmin, Perivasc, Venalot, Varicoss

¹Pearson Chi-squared test ²Student t test with unequal variances; ³Fisher’s exact test; ⁴Multiple answers. *Statisticamiy significant if p < 0.05