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. 2021 May 18;64(8):1822–1833. doi: 10.1007/s00125-021-05468-6

Table 1.

Daily ranges of immune population frequencies and plasma cytokine levels in ten participants with type 1 diabetes

Population Minimum Maximum Mean ICC
Leucocytes (%)
 Granulocyte 8.4 43.3 19.36 43%
 Monocytic leucocytes 8.3 42.2 19.3 43%
Lymphocytes (%)
 B cell 1.2 13.8 4.02 50%
 DC 0.2 0.7 0.34 53%
 Monocyte 2.9 11.2 7.93 69%
  Classical monocyte 3.9 12.8 7.82 49%
  Non-classical monocyte 3.9 12.8 7.82 49%
 NK 1.2 9.4 4.65 21%
  CD56dim 2.6 11.8 6.49 71%
  CD56bright 2.6 11.8 6.49 71%
 NKT 0.2 5.0 0.99 69%
 CD4 T cell 5.3 26.6 11.41 19%
  Naive 2.5 11.7 7.38 94%
  Effector memory 0.9 10.4 5.79 92%
  Central memory 1.5 9.7 5.56 97%
  TEMRA 0.1 5.3 0.93 59%
 Treg 0.4 2.4 0.95 52%
 CD8 T cell 1.7 15.3 5.64 72%
  Naive 3.3 27.1 12.07 85%
  Effector memory 3.6 31.9 10.69 71%
  Central memory 1.2 6.6 3.47 95%
  TEMRA 1.0 6.9 2.78 96%
 CD4CD8 0.5 4.0 1.39 81%
 CD4CD8 0.1 0.7 0.34 61%
 Unidentified 7.3 66.9 20.42 0%
Plasma cytokines (pg/ml)
 IFNγ 0.4 1.7 1.08 83%
 IL-2 0.0 1.5 0.62 84%
 IL-4 2.0 11.9 6.12 89%
 IL-6 1.1 5.2 2.21 73%
 IL-12 0.1 0.9 0.37 80%

For each component, data presented are minimum, maximum and mean of the ranges found across all time points in each of the participants

ICC, intraclass correlation