Table 3.

Plasma cytokine circadian peak level and time of peak in participants with type 1 diabetes

Plasma cytokine	Circadian rhythmicity	Peak (SD units)	95% CI	Time of peaka	95% CI
IFNγ		0.20	0.01, 0.42	17:45	04:39, 23:38
IL-2		0.21	0.01, 0.43	17:14	04:45, 23:06
IL-4		0.15	0.01, 0.30	18:14	02:46, 23:50
IL-6	†	0.51	0.23, 0.85	20:22	17:30, 22:30
IL-12		0.33	0.15, 0.78	18:07	09:20, 22:29

^a24 h clock time

^†Statistically significant, p < 0.05