Table 2.

SNPs with an OR above 1.10 that were associated with type 1 diabetes

Gene	SNP details				Validated eQTL p value in whole blood	Predicted eQTL p value in pancreas	Predicted eQTL p value in whole blood
	SNP	p value (without Q value filtering)	OR (minor allele)	OR (major allele)
IFIH1a	rs77088072b	9.94 × 10−3	0.793	1.261		1.40 × 10−3	4.30 × 10−3
	rs984971	2.40 × 10−16	0.849	1.178			2.50 × 10−2
	rs2068330	3.64 × 10−16	0.850	1.177			2.30 × 10−2
	rs3788964	3.99 × 10−9	0.858	1.165		2.80 × 10−2
	rs1549020b	2.56 × 10−12	0.863	1.158			4.80 × 10−3
	rs3747517	4.98 × 10−11	0.871	1.148		3.50 × 10−2	2.20 × 10−2
	rs13422767	5.33 × 10−8	0.873	1.146		1.50 × 10−2
	rs13023380	2.56 × 10−12	0.876	1.142			4.60 × 10−2
	rs7608315	9.56 × 10−11	0.884	1.131			2.50 × 10−2
	rs13022749b	1.60 × 10−8	0.893	1.120			5.10 × 10−3
IFNAR1a	rs2834136b	1.36 × 10−2	0.854	1.171
IFNGa	rs7132610b	3.18 × 10−3	1.125	0.889
IL1R1	rs79184888b	5.83 × 10−3	0.753	1.328
	rs7565504b	6.70 × 10−3	0.754	1.326
	rs6731416b	6.70 × 10−3	0.754	1.326
	rs140672656b	6.33 × 10−3	0.784	1.275
IRF7a	rs118067545b	8.48 × 10−3	0.836	1.196
	rs3993797b	1.64 × 10−2	0.887	1.128
OAS1a	rs1034687b	2.16 × 10−7	0.869	1.150	2.19 × 10−11
	rs1015249b	1.25 × 10−7	0.895	1.117	2.7 × 10−13
	rs739744b	1.03 × 10−9	1.123	0.890	1.11 × 10−21
OAS2a	rs1034687b	2.16 × 10−7	0.869	1.150
	rs4767000b	1.03 × 10−9	1.123	0.890
	rs739744b	1.03 × 10−9	1.123	0.890
OAS3a	rs1034687b	2.16 × 10−7	0.869	1.150		1.30 × 10−2
	rs739744b	1.03 × 10−9	1.123	0.890	1.32 × 10−4
SP1	rs17125267b	1.03 × 10−2	0.838	1.194
	rs11170466	1.47 × 10−5	1.184	0.845

The SNPs in this table were selected based on their eQTL p value in the specific tissues and their OR being above 1.10 for either the minor or the major allele

^aGenes that also showed dysregulation on RNA expression level

^bNewly discovered in association with type 1 diabetes