Table 2.

Standardised regression coefficients of SD and mean sensor glucose in the fully adjusted models with arterial outcome variables

Arterial outcome variable	Ridge regression penalisation (λ)	SDCGM (st.β, 95% CI)	p value	MSGCGM (st.β, 95% CI)	p value
cf-PWV, SD (n = 643)	λ = 0.11	0.065 (−0.018, 0.167)	0.160	0.059 (−0.043, 0.164)	0.272
carDC, SD (n = 725)	λ = 0.12	−0.003 (−0.097, 0.092)	0.952	0.088 (−0.014, 0.184)	0.102
cIMT, SD (n = 726)	λ = 0.12	−0.007 (−0.123, 0.111)	0.916	0.078 (−0.038, 0.207)	0.198
ABI, SD (n = 816)	λ = 0.11	−0.033 (−0.071, 0.002)	0.060	−0.008 (−0.032, 0.017)	0.548
CWSmean, SD (n = 725)	λ = 0.12	−0.059 (−0.169, 0.066)	0.318	0.082 (−0.044, 0.204)	0.180
CWSpuls, SD (n = 725)	λ = 0.12	−0.045 (−0.145, 0.053)	0.374	0.042 (−0.055, 0.138)	0.410

Associations were adjusted for age, sex, educational level, BMI, smoking status, alcohol use, total-to-HDL-cholesterol levels, use of antihypertensive and lipid-modifying drugs, and the other CGM-assessed index. Further, cf-PWV was additionally adjusted for MAP and heart rate; carDC and CWS_puls were additionally adjusted for MAP; cIMT was additionally adjusted for office systolic BP; ABI was additionally adjusted for office systolic BP and heart rate; and CWS_mean was additionally adjusted for brachial pulse pressure. All coefficients were estimated by use of ridge regression. Point estimates and 95% CIs were calculated by use of 1000 bootstrap estimates

Standardised regression coefficients (st.β) indicate the median difference (95% CI) associated with 1 SD higher SD_CGM or MSG_CGM

In the cf-PWV study population, 1 SD corresponds to 0.57 mmol/l for SD_CGM, 1.3 mmol/l for MSG_CGM, and 2.2 m/s for cf-PWV. In the carDC, cIMT, and CWS study populations, 1 SD corresponds to 0.57 mmol/l for SD_CGM, 1.3 mmol/l for MSG_CGM, 6.0 10⁻³/kPa for carDC, 152.7 μm for cIMT, 10.2 kPa for CWS_mean, and 6.6 kPa for CWS_puls. In the ABI study population, 1 SD corresponds to 0.56 mmol/l for SD_CGM, 1.3 mmol/l for MSG_CGM, and 0.11 for ABI