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. 2021 Jun 30;11:13562. doi: 10.1038/s41598-021-92112-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Random Forest plot representing the distribution of minimal depth and its mean for the indicated groups of samples. (A) Control versus ALS at baseline, (B) Control versus ALS at follow-up, (C) ALS at baseline versus ALS at follow-up, (D) Control versus PLS at baseline, (E) Control versus PLS at follow-up, (F) PLS at baseline PLS at follow-up, (G) Pooled ALS samples versus pooled PLS samples. Species also identified by oPLS-DA are shown in bold.