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Determining new cutoff value for FIB-4 in diagnosing advanced fibrosis.
| Cutoff | Youden’s index | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | |
|---|---|---|---|---|---|---|
| FIB-4 | 1.54 | 0.36 | 90 | 46.7 | 27.7 | 95.3 |
| 3.53 | 0.46 | 56.1 | 90 | 55.8 | 90 | |
| 2.68 | 0.49 | 70.7 | 79.1 | 43.5 | 92.2 |
Advanced fibrosis was defined as liver stiffness greater than 4 kPa. PPV positive predictive value, NPV negative predictive value.
